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CY, DH and WS conceived and designed the review

To recap for asthma: T2-high asthma is associated with Th2 responses T2-low asthma may involve Th1 or Th17 responses, or other non-T2 mechanisms Pathogens as a cause of asthma and as a trigger for exacerbation Bacterial and viral infections may be involved in T2-low asthma as a cause or as a trigger for asthma exacerbations

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One study noted density improvements of 30-40% over 2-6 months of consistent copper peptide application