1 2 3 4 5 "Glucagon-like peptide analogues for type 2 diabetes mellitus"
Standard dosing begins at 0.25 mg weekly, increasing to 0.5 mg after four weeks
- The Double Win: Up to 64% of participants hit a meaningful composite target: an HbA1c of 6.5% AND a weight reduction of 10%
When considering study drug discontinuation or use of rescue medication (trial product estimand results), the weight loss resulting from the use of oral semaglutide was up to 5 kg, while that associated with other active comparators ranged from 0.8 to 3.8 kg, and that associated with placebo ranged from 0.1 to + 0.6 kg [35,36,37,38,39,40]
For a fuller picture of how it fits into a broader plan, see our overview of medical weight loss