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When there was high heterogeneity, random-effects model was selected

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But when inflammation is severe or chronic, it becomes excessive and damages the body its meant to protect.6 Unless you get it back under control, it can contribute to serious health complications down the line cardiovascular diseases, chronic obstructive pulmonary disease, cancer, and Alzheimers, to name a few.7 KPVs role as a treatment is to prevent those complications from arising or worsening

Meanwhile Caremark argues that these controls are necessary both to prevent inappropriate use and to protect health plans from unsustainable cost spikes

That is exactly why I put them first