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Unlike metformin, which has a well-established association with vitamin B12 malabsorption through interference with calcium-dependent B12-intrinsic factor complex absorption in the terminal ileum, there is no official link between GLP-1 receptor agonists and direct B12 depletion

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When combined with strength, nutrition, and long-term lifestyle changes, GLP-1 therapy can support healthier arteries, a more resilient heart, and lower cardiovascular risk over time