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Probably the most severely damaged red blood cells hemolyze in the bloodstream on their own, whereas less severely damaged red blood cells will be recognized as abnormal by macrophages and will undergo extravascular hemolysis in the reticuloendothelial system
Serum trimethylamine-N-oxide is elevated in CKD and correlates with coronary atherosclerosis burden
no expression of GFAP, multiCK, CD45
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