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Possible Side Effects of Semaglutide and Considerations Common Side Effects: While semaglutide is generally well-tolerated, some individuals may experience side effects, such as nausea, diarrhea, constipation, and in rare cases, more serious gastrointestinal issues

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Studies suggest that sema helps lower both fasting and postprandial glucose levels by improving insulin sensitivity, reducing hepatic glucose output, and delaying gastric emptying, which collectively help flatten glucose spikes after meals

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participation in an investigational drug trial in the 3 months before administration of the initial dose of ARA 290 or more than four times per year