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Previous studies showed that overexpression of FOXO1/3a in muscle was associated with remarkable decreases in myotube diameter and fiber size in mice [57]

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Fortunately, a number of natural compounds such as omega-3 fatty acids , vitamin D , pycnogenol, and peony extract may confer benefits for psoriasis patients, protect against adverse effects of some psoriasis treatments, and reduce the risk of cardiovascular and other chronic diseases often associated with psoriasis (Millsop 2014