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In vivo, we validated a significant reduction in tumor growth in the group receiving sertraline together with RT, which was accompanied with reduced glycine/threonine and an accumulation of homocysteine blood serum levels

The presence of endotoxins in the bloodstream can lead to various adverse effects, including sepsis, systemic inflammatory response syndrome (SIRS), and the worsening of already existing diseases like liver dysfunction, renal failure, and acute respiratory distress syndrome (ARDS)

This means the topical evidence, while real, is itself of modest strength

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