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In theory, an increase in the cytosolic Ca 2+ concentration of an erythrocyte may be the consequence of Ca 2+ influx from the extracellular space, decreased Ca 2+ transport from the cytosol to the extracellular space, or release from intracellular Ca 2+ binders

They also play a role in maintaining physiological homeostasis, such as cognition, blood pressure, feeding behavior, water balance, glucose metabolism, pain, and response to stress [7]

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