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Description

Hazan S, Spradling-Reeves KD, Papoutsis A, Walker SJ

Activation of the NLRP3 inflammasome leads to the cleavage of procaspase-1 into its active form, which in turn processes proinflammatory cytokines such as IL-1 and IL-18 and drives pyroptotic cell death via Gasdermin D activation

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Vitamin C neutralizes the damaging effects of ROS, reduces the harmful effects caused by free radicals and regulates collagen production

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